If you do not have a severe form of acne like cystic acne, then an over-the-counter overnight acne treatment can be quite effective. Several different factors can cause acne in teens or adults, such as hereditary, diet, hormones, and skincare products. The most difficult part is finding an over-the-counter acne medication that works without causing other issues to your skin, such as itching or bumps. A team from the Mayo Clinic reviewed hundreds of over-the-counter products in search of the best acne treatments. They looked at reported results, active ingredients for quality, natural extract ingredients, and reported incidents of side effects. They also investigated product reviews online, and after considering the information with doctors, they determined the top three over-the-counter acne treatment products are Exposed Skin Care, ZenMed Derma Cleanse, and ClearPores. Keep reading to learn the top eight questions and answers about acne treatments, so you can choose the one that's right for you.